Janssen Research and Development (R&D), L.L.C., a member of Johnson & Johnson’s Family of Companies, is seeking an Associate Scientist for Biophysics group in Janssen Biotherapeutics (JBIO) located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.

We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Associate Scientist will be part of a team of scientists utilizing a broad spectrum of biophysical techniques to characterize physical attributes of therapeutic assets developed by JBIO, from initial hit generation through lead molecule selection, concluding in the delineation of the biophysical and structural quality of clinical candidates entering the development portfolio. The Associate Scientist is a laboratory-based position that will contribute to the Biophysics team by conducting binding affinity and kinetic assays, such as Surface Plasmon Resonance (SPR) and Biolayer Interferometry (BLI). The Associate Scientist might conduct additional characterizations to assess protein purity and stability using chromatography, light scattering, spectrometric and calorimetric techniques. The associate Scientist will collect, interpret, and report a range of biophysical data and present to manager and project teams in order support lead molecule selection. The associate Scientist is expected to be self-driven, organized, and have excellent analytical and interpersonal skills.

Key Responsibilities

• Set day-to-day objectives and perform complex tasks and procedures related to measuring protein binding interactions and other biophysical properties.
• Perform assigned scientific experiments with minimal level of supervisor’s assistance and ensure timely completion of multiple concurrent experiments.
• Independently analyze and interpret data. Draft technical reports and summary reports for presentations.
• Communicate and present experimental results to manager and project teams in a timely manner.
• Maintain accurate recording of experimental data with the use of standard databases and electronic notebook.
• Identify and troubleshoot instrumentation and experimental problems.
• Maintain and operate laboratory equipment and inventory.
• Function as Biophysics representative on project teams. Interact effectively with multidisciplinary subject matter experts to solve complex challenges and advance discovery efforts.

Qualifications

• M.S. or B.S./B.A. in biochemistry, analytical chemistry, biophysics, structural biology, or related fields is required
• Minimum of 1 year of lab-based pharmaceutical or equivalent experience is required.
• Minimum of 1 year experience using SPR and BLI to study binding properties of antibodies and related therapeutic molecules is preferred.
• Experience with additional biophysical and analytical techniques, including chromatography, light scattering, electrophoresis, spectrometry, or calorimetry is preferred.
• Experience with HTP biophysical characterization and lab automation is preferred.
• Solid understanding of protein biochemistry, antibody structure, and analytical/biophysical characterization of biologics is preferred.
• Strong organizational and communication skills are required.
• This position requires full time presence in our labs located in Spring House, PA.

Primary Location
United States-Pennsylvania-Spring House-Welsh & McKean Roads
Organization
Janssen Research & Development, LLC (6084)
Job Function
R&D
Requisition ID
2105956537W